Product Name: 3,4,5-Trimethoxy Benzoic Acid
Chemical Formula: C10H12O5
Synonyms: Gallic acid trimethyl ether, Eudesmic acid
CAS Number: 118-41-2
Recommended Use: Laboratory chemicals, research and development
Manufacturer Information: Details should be found on the product label or packaging.
Contact Details for Emergency: Poison Control Center or local emergency services.
GHS Classification: Not classified as hazardous under GHS criteria for solid organic acids.
Physical Hazards: May cause irritation to eyes and skin.
Health Hazards: Dusts may be irritating to the respiratory tract if inhaled. Prolonged exposure can produce mild symptoms in sensitive individuals.
Environmental Hazards: Harmful to aquatic life if released in large quantities.
Warning Symbols: No pictogram required by GHS.
Signal Word: None required.
Hazard Statements: Causes skin and eye irritation in concentrated form. Avoid generating dust.
Chemical Identity: 3,4,5-Trimethoxy Benzoic Acid
Common Name: Eudesmic acid
CAS Number: 118-41-2
Concentration: ≥99% (typical high-purity lab-grade sample)
Impurities: Trace organic impurities stemming from synthesis, not likely to pose additional hazard under recommended handling.
Eye Contact: Rinse gently with clean water for 10-15 minutes, keeping eyelids apart. Seek medical attention if irritation continues.
Skin Contact: Wash skin thoroughly with soap and water. Remove contaminated clothing and wash before reuse.
Inhalation: Move to fresh air. Offer respiratory support as needed. Seek attention if breathing problems develop.
Ingestion: Rinse mouth. Drink plenty of water. Do not induce vomiting unless directed by medical staff. Seek medical help if symptoms appear.
Important Symptoms: Irritation, mild cough, redness, rare allergic responses.
Immediate Medical Aid: Unlikely to be needed except for sensitive or exposed individuals.
Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide. Water spray can knock down dust.
Specific Hazards: Burning releases carbon oxides and methoxy fragments. Dust may form explosive mixtures in air.
Protective Equipment: Firefighters always wear self-contained breathing apparatus and full protective clothing to avoid exposure to fumes.
Further Advice: Avoid breathing dust or combustion byproducts. Keep containers cool with water spray if exposed to fire.
Personal Precautions: Use appropriate personal protective gear such as gloves, safety goggles, and mask. Avoid breathing dust.
Environmental Precautions: Prevent spills from entering drains, watercourses, or soil.
Cleaning Methods: Pick up spill using dry methods, collecting material into sealable containers for disposal. Clean area thoroughly with water after material is contained. Use vacuum systems with HEPA filtration or damp sweeping to minimize dust.
Notification: Report significant spills under local regulations if they occur.
Handling: Use in areas with good ventilation. Avoid contact with eyes or prolonged exposure to skin. Do not eat, drink, or smoke while handling. Minimize dust generation and accumulation.
Storage: Store in tightly closed container away from moisture, strong bases, strong oxidizing agents. Protect from direct sunlight and sources of ignition. Store at room temperature in a dry, cool, well-ventilated area. Keep container labeled and out of reach of unauthorized personnel.
Special Sensitivities: Material sensitive to moisture, recommended storage in a desiccator if long term integrity is critical.
Permissible Exposure Limits: No occupational exposure limits assigned for this material. Control dust levels as matter of good laboratory safety.
Engineering Controls: Laboratory fume hood or local exhaust recommended. Maintain basic hygiene and avoid creating dust clouds.
Personal Protective Equipment:
Gloves (nitrile, PVC or similar)
Safety goggles or face shield
Lab coat or protective clothing
Respirator or dust mask if airborne concentrations may exceed safe levels
Hygiene Measures: Always wash hands after handling and before breaks or meals.
Appearance: White to off-white crystalline powder
Odor: Nearly odorless
pH: Slightly acidic in solution
Melting Point: 181-185°C
Boiling Point: Not volatile at atmospheric pressure
Solubility: Poorly soluble in water, readily soluble in alcohol and organic solvents
Vapor Pressure: Negligible
Relative Density: 1.37 – 1.39 g/cm³
Partition Coefficient (log Kow): 1.20 (estimated)
Flash Point: No data, expected to be above 100°C
Evaporation Rate: Not significant
Flammability: Not classed as flammable but organic dust can pose a combustion risk in air
Auto-ignition Temperature: Data not available; handle away from heat sources.
Stability: Stable under recommended storage conditions. Stores well when protected from moisture.
Reactivity: Non-reactive under normal handling conditions.
Incompatible Materials: Bases, strong oxidizers, reducing agents.
Decomposition Products: Carbon dioxide, carbon monoxide, various organic fragments under thermal decomposition.
Hazardous Reactions: Does not undergo hazardous reactions under expected conditions.
Polymerization: Not a concern with this substance.
Acute Toxicity: Oral LD50 (rat) above 2000 mg/kg (estimated, low toxicity).
Inhalation: Dust irritation possible; systemic effects unlikely with normal care.
Skin Contact: May cause mild irritation on prolonged contact.
Eye Contact: Can cause mild to moderate irritation.
Chronic Exposure: No data suggesting systemic health effects in humans; avoid long-term unnecessary exposure.
Sensitization: No human sensitization data, similar compounds have low risk.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No components listed as hazardous by IARC, NTP or OSHA.
Ecotoxicity: Not considered acutely toxic to aquatic organisms based on minimally available data. Spills in concentrated form can disturb local ecosystems.
Persistence and Degradability: Expected to break down over time through natural processes but not readily biodegradable.
Bioaccumulation Potential: Low based on structure.
Mobility in Soil: Tends to bind to soil particles, unlikely to leach.
Other Adverse Effects: Avoid uncontrolled release to the environment, especially waterways.
Waste Disposal Methods: Place contaminated material and residues in sealed, labeled containers for chemical waste pickup.
Unwanted product: Consign to facility licensed for chemical waste.
Contaminated Packaging: Rinse containers, dispose in line with local and national regulations.
Precautions: Prevent entry into drains or natural water bodies; follow best chemical hygiene practices.
UN Number: Not regulated for road, rail, air, or sea transport.
Proper Shipping Name: Not regulated (chemical substance, not hazardous for transport under current regulations).
Transport Hazard Class: Not applicable.
Packing Group: Not applicable.
Environmental Hazards: Not a marine pollutant.
Special Transport Precautions: Package securely, keep container closed during transport, avoid excessive vibration, protect from moisture and physical damage.
Safety, Health, and Environmental Regulations: Not listed as a hazardous substance under TSCA, REACH, or major regulatory frameworks.
Labeling Requirements: No hazard labeling required, keep clear identification on all containers.
Workplace Controls: General chemical safety practices apply; refer to local labor protection standards.
Inventory Status: Exempt or listed in national and major international inventories (check specific jurisdiction for updates).
Other Restrictions: None identified for laboratory or research use.
